AD-EEGWA Project

Activity 1. Selection of subjects and data collection.

Selection of the sample that will participate in the study (250 subjects taken from both areas of project intervention, divided as follows: 150 patients with Alzheimer's disease at mild, moderate and severe stages, 50 subjects with mild cognitive impairment and 50 controls), plus a collection of their biological samples (buccal mucosa) and their brain activity (electroencephalogram, EEG).

Activity 2. Genome and brain activity analysis .

Obtaining the genetic profiles of the participants from the biological material collected in the previous activity, and analysis of the EEG recordings by means of advanced signal processing methods.

Activity 3. Correlation between the genome and the EEG.

Pattern identification by means of meta-analysis, providing assistance in the diagnosis of Alzheimer's disease. This will be carried out combining EEG signals and genetic data from all the participants in the study.

Activity 4. Conclusions.

Design of a tool to help in the diagnosis of Alzheimer's disease, based on the analysis carried out in the previous activities. Additionally, we will evaluate the possible exploitation of the aforementioned tool.

Activity 5. Management and coordination.

Coordination and supervision of each activity by the main beneficiary, each institution being responsible for their own actions.

Activity 6. Communication.

Participation in conferences to present the preliminary results of the project to the scientific community, publication of papers showing the final results in prestigious international journals, and preparation of communication material to make society aware of the progress of the project (website, social networks, preparation of seminars and press releases).